Intracellular receptor
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Intracellular receptors are receptors located inside the cell rather than on its cell membrane. Examples are the class of nuclear receptors located in the cell nucleus and the IP3 receptor located on the endoplasmic reticulum. The ligands that bind to them are usually intracellular second messengers like inositol trisphosphate (IP3) and extracellular lipophilic hormones like steroid hormones.
Contents |
[edit] Members
[edit] Transcription factors
- Steroid hormone receptor:
- Sex hormone receptors (sex hormones)
- Estrogen receptor (α and β)
- Androgen receptor (one type)
- Vitamin D receptor (vitamin D, one type)
- Glucocorticoid receptor (glucocorticoids, one type)
- Mineralocorticoid receptor (mineralocorticoids, one type)
- Sex hormone receptors (sex hormones)
- Thyroid hormone receptor (α and β)
- Retinoic acid receptor (vitamin A and related compounds);
- Peroxisome proliferator-activated receptors (PPARs, α, γ and δ)
- Retinoid X receptor
- Farnesoid X receptor
- Liver X receptor
- Pregnane X receptor
- Constitutive androstane receptor
[edit] Various
[edit] See also
[edit] External links
- Nuclear Receptor journal homepage
- Nuclear receptor resource at Georgetown University
- Nuclear receptor signalling atlas (NURSA, open-access journal)
Constitutive androstane receptor - Core binding factor - E2F - Farnesoid X receptor - Kruppel-like factors - Nanog - NF-kB - Oct-4 - P300/CBP - Peroxisome proliferator-activated - PIT-1 - Rho factor - R-SMAD - Sigma factor - Sox2 - Sp1 - STAT protein
Basic-helix-loop-helix: Aryl hydrocarbon receptor - Hypoxia inducible factors - MYC - MyoD - Myogenin - Twist transcription factor
Basic leucine zipper: Ccaat-enhancer-binding proteins - CREB -
Basic helix-loop-helix leucine zipper: Microphthalmia-associated transcription factor - Sterol regulatory element binding protein
Steroid hormone receptors
Type I:
Glucocorticoid receptor -
Mineralocorticoid receptor -
Sex hormone receptor (Androgen receptor, Estrogen receptor, Progesterone receptor)
Type II:
Calcitriol receptor -
Retinoid receptor (Retinoic acid receptor, Retinoid X receptor) -
Thyroid hormone receptor
See also: Intracellular receptors, Nuclear receptor
Cell physiology: cell signaling | |
|---|---|
| Key concepts | Ligand - Cell signaling networks - Signal transduction - Apoptosis - Second messenger system (Ca2+ signaling, Lipid signaling) |
| Processes | Paracrine - Autocrine - Juxtacrine - Neurotransmitters - Endocrine (Neuroendocrine) |
| Types of proteins | Receptor (Transmembrane, Intracellular) - Transcription factor (General, Preinitiation complex, TFIID, TFIIH) - Adaptor protein |
| This page uses content from the English-language version of Wikipedia. The original article was at Intracellular receptor. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License. |
