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Interposed nucleus

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Brain: Interposed nucleus
[[Image:|250px|center|]]
[[Image:|250px|center|]]
Latin nucleus interpositus anterior, nucleus interpositus posterior
Gray's subject #
Part of
Components
Artery
Vein
BrainInfo/UW -
MeSH [1]

The interposed nucleus is a deep nucleus of the cerebellum and is composed of the globose nuclei and the emboliform nuclei. It is located in in the roof (dorsal aspect) of the fourth ventricle, lateral to the fastigial nucleus. It receives its afferent supply from the anterior lobe of the cerebellum and sends output via the superior cerebellar peduncle to the red nucleus.

FunctionEdit

Functionally, it modulates muscle stretch reflexes of distal muscle groups.

External linksEdit


Template:Cerebellum

v·d·e
Brain and spinal cord: neural tracts and fasciculi
Sensory/
ascending

1°: Pacinian corpuscle/Meissner's corpuscle → Gracile fasciculus/Cuneate fasciculus → Gracile nucleus/Cuneate nucleus

2°: → sensory decussation/arcuate fibers (Posterior external arcuate fibers, Internal arcuate fibers) → Medial lemniscus/Trigeminal lemniscus → Thalamus (VPL, VPM)

3°: → Posterior limb of internal capsule → Postcentral gyrus


Fast/lateral

1° (Free nerve ending → A delta fiber) → 2° (Anterior white commissure → Lateral and Anterior Spinothalamic tract → Spinal lemniscus → VPL of Thalamus) → 3° (Postcentral gyrus) → 4° (Posterior parietal cortex)

2° (Spinotectal tract → Superior colliculus of Midbrain tectum)

Slow/medial

1° (Group C nerve fiber → Spinoreticular tract → Reticular formation) → 2° (MD of Thalamus) → 3° (Cingulate cortex)


Motor/
descending

Pyramidal

flexion: Primary motor cortex → Posterior limb of internal capsule → Decussation of pyramids → Corticospinal tract (Lateral, Anterior) → Neuromuscular junction

flexion: Primary motor cortex → Genu of internal capsule → Corticobulbar tract → Facial motor nucleus → Facial muscles

flexion: Red nucleus → Rubrospinal tract

extension: Vestibulocerebellum → Vestibular nuclei → Vestibulospinal tract

extension: Vestibulocerebellum → Reticular formation → Reticulospinal tract

Midbrain tectum → Tectospinal tract → muscles of neck

direct: 1° (Motor cortex → Striatum) → 2° (GPi) → 3° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 4° (Thalamocortical radiations → Supplementary motor area) → 5° (Motor cortex)

indirect: 1° (Motor cortex → Striatum) → 2° (GPe) → 3° (Subthalamic fasciculus → Subthalamic nucleus) → 4° (Subthalamic fasciculus → GPi) → 5° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 6° (Thalamocortical radiations → Supplementary motor area) → 7° (Motor cortex)

nigrostriatal pathway: Pars compacta → Striatum


Cerebellar

Afferent

Vestibular nucleus → Vestibulocerebellar tract → ICP → Cerebellum → Granule cell

Pontine nuclei → Pontocerebellar fibers → MCP → Deep cerebellar nuclei → Granule cell

Inferior olivary nucleus → Olivocerebellar tract → ICP → Hemisphere → Purkinje cell → Deep cerebellar nuclei

Efferent

Dentate nucleus in Lateral hemisphere/pontocerebellum → SCP → Dentatothalamic tract → Thalamus (VL) → Motor cortex

Interposed nucleus in Intermediate hemisphere/spinocerebellum → SCP → Reticular formation, or → Cerebellothalamic tract → Red nucleus → Thalamus (VL) → Motor cortex

Fastigial nucleus in Flocculonodular lobe/vestibulocerebellum → Vestibulocerebellar tract → Vestibular nucleus

Bidirectional:
Spinocerebellar

lower limb → 1° (muscle spindles → DRG) → 2° (Posterior thoracic nucleus → Dorsal/posterior spinocerebellar tract → ICP → Cerebellar vermis)

upper limb → 1° (muscle spindles → DRG) → 2° (Accessory cuneate nucleus → Cuneocerebellar tract → ICP → Anterior lobe of cerebellum)

lower limb → 1° (Golgi tendon organ) → 2° (Ventral/anterior spinocerebellar tract→ SCP → Cerebellar vermis)

upper limb → 1° (Golgi tendon organ) → 2° (Rostral spinocerebellar tract → ICP → Cerebellum)


Template:Central nervous system navs
[[[:Template:Fullurl:Template:]] v]·[[[:Template:Fullurl:Template talk:]] d]·[[[:Template:Fullurl:Template:]] e]

M: PNS

proc, drug(N1B)

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