Wikia

Psychology Wiki

Inositol triphosphate receptor

Talk0
34,135pages on
this wiki
Revision as of 08:16, March 14, 2007 by Dr Joe Kiff (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


inositol 1,4,5-triphosphate receptor, type 1
Symbol(s): ITPR1
Locus: 3 p26.1
EC number [1]
EntrezGene 3708
OMIM 147265
RefSeq NM_002222
UniProt Q14643
inositol 1,4,5-triphosphate receptor, type 2
Symbol(s): ITPR2
Locus: 12 p11.23
EC number [2]
EntrezGene 3709
OMIM 600144
RefSeq NM_002223
UniProt Q14571
inositol 1,4,5-triphosphate receptor, type 3
Symbol(s): ITPR3
Locus: 6 p21.31
EC number [3]
EntrezGene 3710
OMIM 147267
RefSeq NM_002224
UniProt Q14573

Inositol triphosphate receptor (IP3R) is a membrane glycoprotein complex acting as Ca2+ channel activated by inositol triphosphate (IP3).

DistributionEdit

It has a broad tissue distribution but is especially abundant in the cerebellum. Most of the IP3R's are found in the cell integrated into the endoplasmic reticulum.

StructureEdit

The IP3R complex is formed of four 313 kDa subunits. There are 3 isoforms and these can form homo- or hetero-oligomers.

See alsoEdit

External linksEdit



This page uses Creative Commons Licensed content from Wikipedia (view authors).

Around Wikia's network

Random Wiki