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In biochemistry, indoleamines are substituted indole compounds that contain an indole ring with five members and an amino group (NH2). Examples of indoleamines are serotonin, tryptamines and the lysergamides. Another example of an indolamine is melatonin, which regulates the sleep-wake cycle (circadian rhythm) in humans.

They are a family of biogenic amines which act as neurotransmitters that share a common molecular structure (namely, indolamine). and are involved in mood and sleep.

In biochemistry, indoleamines are substituted indole compounds that contain an amino group. Examples of indoleamines include the lysergamides.

Synthesis Edit

File:Serotonin biosynthesis.svg

In humans, neurotransmitters in the indolamine family are believed to be produced in the pineal gland.[citation needed] Indolamines are biologically synthesized from the essential amino acid tryptophan.

See also Edit


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