ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseases

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Contents 1 E00-E35 - Endocrine diseases 1.1 (E00-E07) Thyroid gland / Thyroid hormone 1.2 (E10-E16) Pancreas / Insulin, glucagon 1.2.1 (E10-E14) Diabetes mellitus 1.2.2 (E15-E16) Other disorders of glucose regulation and pancreatic internal secretion 1.3 (E20-E21) Parathyroid gland / PTH 1.4 (E22-E23) Pituitary gland / ADH, oxytocin, GH, ACTH, TSH, LH, FSH, prolactin 1.5 (E24-E27) Adrenal gland / Aldosterone, cortisol, epinephrine, norepinephrine 1.6 (E28-E30) Gonads / Estrogen, androgens, testosterone, etc. 1.7 (E31-E35) Other 2 E40-68 - Nutritional diseases 2.1 (E40-E46) Malnutrition 2.2 (E50-E64) Other nutritional deficiencies 2.3 (E65-E68) Obesity and other hyperalimentation 3 E70-E90 - Metabolic diseases 3.1 (E70-E79) Metabolic disorders of proteins, fats, and carbohydrates 3.1.1 (E70-E72) Amino-acids 3.1.2 (E73-E74) Carbohydrates 3.1.3 (E75) Lipids 3.1.4 (E76-E78) Combinations 3.2 (E79-E90) Other metabolic disorders 4 See also

[edit] E00-E35 - Endocrine diseases

[edit] (E00-E07) Thyroid gland / Thyroid hormone

• (E00) Congenital iodine-deficiency syndrome

• (E01) Iodine-deficiency-related thyroid disorders and allied conditions
  • (E010) Iodine-deficiency-related diffuse (endemic) goitre
  • (E011) Iodine-deficiency-related multinodular (endemic) goitre
  • (E012) Iodine-deficiency-related (endemic) goitre, unspecified
  • (E018) Other iodine-deficiency-related thyroid disorders and allied condition

• (E02) Subclinical iodine-deficiency hypothyroidism
• (E03) Other hypothyroidism
  • (E030) Congenital hypothyroidism with diffuse goitre
  • (E031) Congenital hypothyroidism without goitre
  • (E032) Hypothyroidism due to medicaments and other exogenous substances
  • (E033) Postinfectious hypothyroidism
  • (E034) Atrophy of thyroid (acquired)
  • (E035) Myxoedema coma
• (E04) Other nontoxic goitre

• (E05) Thyrotoxicosis (hyperthyroidism)
  • (E050) Thyrotoxicosis with diffuse goitre
    • Graves' disease
  • (E051) Thyrotoxicosis with toxic single thyroid nodule
  • (E052) Thyrotoxicosis with toxic multinodular goitre
  • (E053) Thyrotoxicosis from ectopic thyroid tissue
  • (E054) Thyrotoxicosis factitia
  • (E055) Thyroid crisis or storm
  • (E058) Other thyrotoxicosis
  • (E059) Thyrotoxicosis, unspecified

• (E06) Thyroiditis
  • (E060) Acute thyroiditis
  • (E061) Subacute thyroiditis
    • De Quervain's thyroiditis
  • (E062) Chronic thyroiditis with transient thyrotoxicosis
  • (E063) Autoimmune thyroiditis
    • Hashimoto's thyroiditis
  • (E064) Drug-induced thyroiditis
  • (E065) Other chronic thyroiditis
  • (E069) Thyroiditis, unspecified

• (E07) Other disorders of thyroid
  • (E070) Hypersecretion of calcitonin
  • (E071) Dyshormogenetic goitre
  • (E078) Other specified disorders of thyroid
    • Sick-euthyroid syndrome
  • (E079) Disorder of thyroid, unspecified

[edit] (E10-E16) Pancreas / Insulin, glucagon

[edit] (E10-E14) Diabetes mellitus

• Note: the following conditions are subtypes of each code from E10-14:
  • (E1x.0) Diabetic coma
  • (E1x.1) Diabetic ketoacidosis
  • (E1x.2) Diabetic nephropathy
  • (E1x.3) Diabetic retinopathy
  • (E1x.4) Diabetic neuropathy
  • (E1x.5) Diabetic angiopathy
  • (E1x.6) Diabetic arthropathy
• (E10) Insulin-dependent diabetes mellitus
• (E11) Non-insulin-dependent diabetes mellitus
• (E12) Malnutrition-related diabetes mellitus
• (E13) Other specified diabetes mellitus
• (E14) Unspecified diabetes mellitus

[edit] (E15-E16) Other disorders of glucose regulation and pancreatic internal secretion

• (E15) Nondiabetic hypoglycaemic coma
• (E16) Other disorders of pancreatic internal secretion
  • (E160) Drug-induced hypoglycaemia without coma
  • (E161) Other hypoglycaemia
  • (E162) Hypoglycaemia, unspecified
  • (E163) Increased secretion of glucagon
  • (E164) Abnormal secretion of gastrin
    • Hypergastrinaemia
    • Zollinger-Ellison syndrome
  • (E168) Other specified disorders of pancreatic internal secretion
  • (E169) Disorder of pancreatic internal secretion, unspecified

[edit] (E20-E21) Parathyroid gland / PTH

• (E20) Hypoparathyroidism
  • (E200) Idiopathic hypoparathyroidism
  • (E201) Pseudohypoparathyroidism

• (E21) Hyperparathyroidism and other disorders of parathyroid gland
  • (E210) Primary hyperparathyroidism
  • (E211) Secondary hyperparathyroidism, not elsewhere classified

[edit] (E22-E23) Pituitary gland / ADH, oxytocin, GH, ACTH, TSH, LH, FSH, prolactin

• (E22) Hyperfunction of pituitary gland
  • (E220) Acromegaly and pituitary gigantism
  • (E221) Hyperprolactinaemia
  • (E222) Syndrome of inappropriate secretion of antidiuretic hormone
    • Central precocious puberty

• (E23) Hypofunction and other disorders of pituitary gland
  • (E230) Hypopituitarism
    • Fertile eunuch syndrome
    • Hypogonadotropic hypogonadism
    • Idiopathic growth hormone deficiency
    • Isolated deficiency of gonadotropin
    • Isolated deficiency of growth hormone
    • Isolated deficiency of pituitary hormone
    • Kallmann's syndrome
    • Lorain-Levi short stature
    • Necrosis of pituitary gland (postpartum)
    • Panhypopituitarism
    • Pituitary cachexia
    • Pituitary insufficiency NOS
    • Pituitary short stature
    • Sheehan's syndrome
    • Simmonds' disease

• • (E231) Drug-induced hypopituitarism
  • (E232) Diabetes insipidus
  • (E233) Hypothalamic dysfunction, not elsewhere classified

[edit] (E24-E27) Adrenal gland / Aldosterone, cortisol, epinephrine, norepinephrine

• (E24) Cushing's syndrome
  • (E240) Pituitary-dependent Cushing's disease
  • (E241) Nelson's syndrome
  • (E242) Ectopic ACTH syndrome
  • (E243) Alcohol-induced pseudo-Cushing's syndrome
  • (E244) Other Cushing's syndrome
  • (E245) Cushing's syndrome, unspecified

• (E25) Adrenogenital disorders
  • (E250) Congenital adrenogenital disorders associated with enzyme deficiency
    • Congenital adrenal hyperplasia
      • Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

• (E26) Hyperaldosteronism
  • (E260) Primary hyperaldosteronism
    • Conn's syndrome
    • Primary aldosteronism due to adrenal hyperplasia (bilateral)
  • (E261) Secondary hyperaldosteronism
  • (E268) Other hyperaldosteronism
    • Bartter's syndrome
  • (E269) Hyperaldosteronism, unspecified

• (E27) Other disorders of adrenal gland
  • (E270) Other adrenocortical overactivity
  • (E271) Primary adrenocortical insufficiency
    • Addison's disease
  • (E272) Addisonian crisis
  • (E273) Drug-induced adrenocortical insufficiency
  • (E274) Other and unspecified adrenocortical insufficiency
    • Hypoaldosteronism
    • Adrenocortical insufficiency NOS
  • (E275) Adrenomedullary hyperfunction

[edit] (E28-E30) Gonads / Estrogen, androgens, testosterone, etc.

• (E28) Ovarian dysfunction
  • (E280) Estrogen excess
  • (E281) Androgen excess
  • (E282) Polycystic ovarian syndrome
  • (E283) Primary ovarian failure
    • Premature menopause NOS

• (E29) Testicular dysfunction
  • (E290) Testicular hyperfunction
  • (E291) Testicular hypofunction
    • 5-Alpha-reductase deficiency (with male pseudohermaphroditism)
    • Testicular hypogonadism NOS

• (E30) Disorders of puberty, not elsewhere classified
  • (E300) Delayed puberty
  • (E301) Precocious puberty
  • (E308) Other disorders of puberty
    • Premature thelarche

[edit] (E31-E35) Other

• (E31) Polyglandular dysfunction
  • (E310) Autoimmune polyglandular failure
    • Schmidt's syndrome
  • (E311) Polyglandular hyperfunction

• (E32) Diseases of thymus
  • (E320) Persistent hyperplasia of thymus
  • (E321) Abscess of thymus

• (E34) Other endocrine disorders
  • (E340) Carcinoid syndrome
  • (E341) Other hypersecretion of intestinal hormones
  • (E342) Ectopic hormone secretion, not elsewhere classified
  • (E343) Short stature, not elsewhere classified
    • NOS
    • constitutional
    • Laron-type
    • psychosocial
  • (E344) Constitutional tall stature
  • (E345) Androgen resistance syndrome
    • Reifenstein's syndrome
  • (E348) Other specified endocrine disorders
    • Progeria

• (E35) Disorders of endocrine glands in diseases classified elsewhere
  • (E350) Disorders of thyroid gland in diseases classified elsewhere
  • (E351) Disorders of adrenal glands in diseases classified elsewhere
  • (E358) Disorders of other endocrine glands in diseases classified elsewhere

[edit] E40-68 - Nutritional diseases

[edit] (E40-E46) Malnutrition

• (E40) Kwashiorkor
• (E41) Nutritional marasmus
• (E42) Marasmic kwashiorkor
• (E43) Unspecified severe protein-energy malnutrition
• (E44) Protein-energy malnutrition of moderate and mild degree
• (E45) Retarded development following protein-energy malnutrition
• (E46) Unspecified protein-energy malnutrition

[edit] (E50-E64) Other nutritional deficiencies

• (E50) Vitamin A deficiency
  • (E500) Vitamin A deficiency with conjunctival xerosis
  • (E501) Vitamin A deficiency with Bitot's spot and conjunctival xerosis
  • (E502) Vitamin A deficiency with corneal xerosis
  • (E503) Vitamin A deficiency with corneal ulceration and xerosis
  • (E504) Vitamin A deficiency with keratomalacia
  • (E505) Vitamin A deficiency with night blindness
  • (E506) Vitamin A deficiency with xerophthalmic scars of cornea
  • (E507) Other ocular manifestations of vitamin A deficiency
    • Xerophthalmia NOS
• (E51) Thiamine deficiency
  • (E511) Beriberi
  • (E512) Wernicke's encephalopathy
• (E52) Niacin deficiency (pellagra)
• (E53) Deficiency of other B group vitamins
  • (E530) Riboflavin deficiency
    • Ariboflavinosis
  • (E531) Pyridoxine deficiency
  • (E538) Deficiency of other specified B group vitamins
• (E54) Ascorbic acid deficiency
  • Scurvy
• (E55) Vitamin D deficiency
  • (E550) Rickets, active
• (E56) Other vitamin deficiencies
  • (E560) Deficiency of vitamin E
  • (E561) Deficiency of vitamin K
• (E58) Dietary calcium deficiency
• (E59) Dietary selenium deficiency
• (E60) Dietary zinc deficiency
• (E61) Deficiency of other nutrient elements
  • (E611) Iron deficiency
  • (E612) Magnesium deficiency
  • (E613) Manganese deficiency
  • (E614) Chromium deficiency
  • (E615) Molybdenum deficiency
  • (E616) Vanadium deficiency
• (E63) Other nutritional deficiencies
  • (E630) Essential fatty acid (EFA) deficiency
• (E64) Sequelae of malnutrition and other nutritional deficiencies

[edit] (E65-E68) Obesity and other hyperalimentation

• (E65) Localized adiposity
• (E66) Obesity
• (E67) Other hyperalimentation
  • (E670) Hypervitaminosis A
  • (E673) Hypervitaminosis D
• (E68) Sequelae of hyperalimentation

[edit] E70-E90 - Metabolic diseases

[edit] (E70-E79) Metabolic disorders of proteins, fats, and carbohydrates

[edit] (E70-E72) Amino-acids

• (E70) Disorders of aromatic amino-acid metabolism
  • (E700) Classical phenylketonuria
  • (E701) Other hyperphenylalaninaemias
  • (E702) Disorders of tyrosine metabolism
    • Alkaptonuria (ILDS E70.210)
    • Ochronosis (ILDS E70.230)
    • Tyrosinaemia
  • (E703) Albinism
    • Chediak-Higashi syndrome
    • Cross syndrome
    • Hermansky-Pudlak syndrome

• (E71) Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
  • (E710) Maple-syrup-urine disease
  • (E711) Other disorders of branched-chain amino-acid metabolism
    • Propionic acidemia
    • Methylmalonic acidemia
    • Isovaleric acidemia
  • (E712) Disorder of branched-chain amino-acid metabolism, unspecified
  • (E713) Disorders of fatty-acid metabolism
    • Muscle carnitine palmityltransferase deficiency

• (E72) Other disorders of amino-acid metabolism
  • (E720) Disorders of amino-acid transport
    • Cystinuria
    • Cystinosis
    • Hartnup disease
    • Lowe's syndrome
  • (E721) Disorders of sulfur-bearing amino-acid metabolism
    • Cystathioninuria
    • Homocystinuria
    • Methioninaemia
    • Sulfite oxidase deficiency
  • (E722) Disorders of urea cycle metabolism
    • Argininaemia
    • Argininosuccinic aciduria
    • Citrullinaemia
    • Hyperammonaemia
  • (E723) Disorders of lysine and hydroxylysine metabolism
    • Glutaric aciduria
    • Hydroxylysinaemia
    • Hyperlysinaemia
  • (E724) Disorders of ornithine metabolism
    • Ornithinaemia (types I, II)
  • (E725) Disorders of glycine metabolism
    • Hyperhydroxyprolinaemia
    • Hyperprolinaemia (types I, II)
    • Non-ketotic hyperglycinaemia
    • Sarcosinaemia

[edit] (E73-E74) Carbohydrates

• (E73) Lactose intolerance

• (E74) Other disorders of carbohydrate metabolism
  • (E740) Glycogen storage disease
    • Glycogen storage disease type I (von Gierke's disease)
    • Glycogen storage disease type II (Pompe's disease)
    • Glycogen storage disease type III
    • Glycogen storage disease type IV
    • Glycogen storage disease type V (McArdle's disease)
  • (E741) Disorders of fructose metabolism
    • Hereditary fructose intolerance
  • (E742) Disorders of galactose metabolism
    • Galactosaemia

[edit] (E75) Lipids

• (E75) Disorders of sphingolipid metabolism and other lipid storage disorders
  • (E750) GM 2 gangliosidosis
    • Sandhoff disease
    • Tay-Sachs disease
  • (E751) Other gangliosidosis
    • GM 1
    • GM 3
    • Mucolipidosis IV
  • (E752) Other sphingolipidosis
    • Gaucher's disease (ILDS E75.220)
    • Niemann-Pick disease (ILDS E75.230)
    • Farber's disease (ILDS E75.240)
    • Fabry's disease (ILDS E75.250)
  • (E753) Sphingolipidosis, unspecified
  • (E754) Neuronal ceroid lipofuscinosis
    • Batten disease (Type 3)
    • Bielschowsky-Jansky disease (Type 2)
    • Kufs disease (Type 4)
    • Spielmeyer-Vogt disease (Type 3)
  • (E755) Other lipid storage disorders
    • Cerebrotendinous cholesterosis (van Bogaert-Scherer-Epstein)
    • Wolman's disease
  • (E756) Lipid storage disorder, unspecified

[edit] (E76-E78) Combinations

• (E76) Disorders of glycosaminoglycan metabolism
  • (E760) Mucopolysaccharidosis, type I
    • Hurler syndrome
  • (E761) Mucopolysaccharidosis, type II
    • Hunter syndrome
  • (E762) Other mucopolysaccharidoses
    • Sanfilippo syndrome
    • Morquio syndrome

• (E77) Disorders of glycoprotein metabolism
  • (E770) Defects in post-translational modification of lysosomal enzymes
    • Mucolipidosis II (I-cell disease)
    • Mucolipidosis III (pseudo-Hurler polydystrophy)
  • (E771) Defects in glycoprotein degradation
    • Aspartylglucosaminuria
    • Fucosidosis
    • Mannosidosis
    • Sialidosis (mucolipidosis I)

• (E78) Disorders of lipoprotein metabolism and other lipidaemias
  • (E780) Pure hypercholesterolaemia
    • Familial hypercholesterolaemia
    • Fredrickson's hyperlipoproteinaemia, type IIa
    • Hyperbetalipoproteinaemia
    • Hyperlipidaemia, group A
    • Low-density-lipoprotein-type (LDL) hyperlipoproteinaemia
  • (E781) Pure hyperglyceridaemia
    • Endogenous hyperglyceridaemia
    • Fredrickson's hyperlipoproteinaemia, type IV
    • Hyperlipidaemia, group B
    • Hyperprebetalipoproteinaemia
    • Very-low-density-lipoprotein-type (VLDL) hyperlipoproteinaemia
  • (E782) Mixed hyperlipidaemia
    • Broad- or floating-betalipoproteinaemia
    • Fredrickson's hyperlipoproteinaemia, type IIb or III
    • Hyperbetalipoproteinaemia with prebetalipoproteinaemia
    • Hypercholesterolaemia with endogenous hyperglyceridaemia
    • Hyperlipidaemia, group C