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Homovanillic acid (HOC₆H₃(OCH₃)CH₂COOH; synonyms: 3-Methoxy-4-hydroxyphenyl acetic acid; HVA; 4-Hydroxy-3-methoxy-benzeneacetic acid; 4-Hydroxy-3-methoxyphenylacetic acid) is a major catecholamine metabolite. It is used as a reagent to detect oxidative enzymes.

In psychiatry and neuroscience, brain and cerebrospinal fluid levels of HVA are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose.¹

[edit] Notes

• Note 1: Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J. (2006) Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia. Schizophr Res. 86(1-3):45-53. PMID 16806836

ru:Гомованилиновая кислота

This page uses content from the English-language version of Wikipedia. The original article was at Homovanillic acid. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.