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Homovanillic acid

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Homovanillic acid (HOC6H3(OCH3)CH2COOH; synonyms: 3-Methoxy-4-hydroxyphenyl acetic acid; HVA; 4-Hydroxy-3-methoxy-benzeneacetic acid; 4-Hydroxy-3-methoxyphenylacetic acid) is a major catecholamine metabolite.

Dopamine degradation

In psychiatry and neuroscience, brain and cerebrospinal fluid levels of HVA are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose.1

See alsoEdit


Notes Edit

  • Note 1: Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J. (2006) Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia. Schizophr Res. 86(1-3):45-53. PMID 16806836


ru:Гомованилиновая кислота
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