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Histamine receptors

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The histamine receptors are a class of G-protein coupled receptors with histamine as their endogenous ligand.

There are four known histamine receptors:

There are several splice variants of H3 present in various species. Though all of the receptors are 7-transmembrane g protein coupled receptors, H1 and H2 are quite different from H3 and H4 in their activities. H1 causes an increase in phosphoinositol hydrolysis, H2 stimulates gastric acid secretion, and H3 mediates feedback inhibition of histamine.

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Smallwikipedialogo.png This page uses content from the English-language version of Wikipedia. The original article was at Histamine receptor. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.