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HRAS1 is a gene on Chromosome 11

Gerhard et al .found linkage between manic depression and HRAS1 in a single large Amish kindred.

However Hodgkinson et al (2002) could not confirm this in their study of Icelandic families.

See alsoEdit

• HRAS

• Genetic factors in bipolar depression

ReferencesEdit

• Gerhard, D. S. et al.(1984). Am. J. hum. Genet. 36, S35
• Gerhard, D. S. et al.(1986). Symp. Genet. Res. Psychiat. Berlin
• Hodgkinson,S., Sherrington,R., Gurling,H., Marchbanks,R., Reeders,S., Mallet,J., Mclnnis,M., Petursson,H. & Brynjolfsson,J.(2002); Molecular genetic evidence for heterogeneity in manic depression.Nature 325, 805 -806 doi:10.1038/325805a0