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Gerhard et al .found linkage between manic depression and HRAS1 in a single large Amish kindred.
However Hodgkinson et al (2002) could not confirm this in their study of Icelandic families.
See also
HRAS Chromosome 11 (human) Genetic factors in bipolar depression
References
- Gerhard, D. S. et al.(1984). Am. J. hum. Genet. 36, S35
- Gerhard, D. S. et al.(1986). Symp. Genet. Res. Psychiat. Berlin
- Hodgkinson,S., Sherrington,R., Gurling,H., Marchbanks,R., Reeders,S., Mallet,J., Mclnnis,M., Petursson,H. & Brynjolfsson,J.(2002); Molecular genetic evidence for heterogeneity in manic depression.Nature 325, 805 -806 doi:10.1038/325805a0