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In biology, gonochorism (Greek seed + disperse) or unisexualism describes sexually reproducing species in which there are at least two distinct sexes. The sex of an individual is genetically determined and does not change throughout its lifetime. Good examples of this type of pollination are hollies, and kiwifruit. In these plants the male plant which supplies the pollen is referred to as the pollenizer. The vast majority of mammals, for example, are gonochorists.

Gonochorism stands in contrast to other reproductive strategies such as hermaphroditism.

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