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Gliosis

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Gliosis is the replacement of dead neurons with a type of glial cells called astrocytes in damaged areas of the central nervous system (CNS).

Astrocytes are relatively large glial cells and are the connective tissue cells of the CNS. Astrocytes have various functions, including accumulating in areas where nerve cells (neurons) have been damaged. Gliosis and neuronal loss in certain brain regions are findings seen in various neurodegenerative disorders such as Korsakoff's syndrome and AIDS dementia complex.

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