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(Created page with "{{BioPsy}} A '''germline mutation''' is any detectable and heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring,...")
 
 
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{{BioPsy}}
 
{{BioPsy}}
A '''germline mutation''' is any detectable and heritable variation in the lineage of [[germ cell]]s. [[Mutation]]s in these cells are transmitted to [[offspring]], while, on the other hand, those in [[somatic]] cells are not. A germline mutation gives rise to a '''constitutional mutation''' in the offspring, that is, a mutation that is present in virtually every cell. A constitutional mutation can also occur very soon after [[fertilisation]], or continue from a previous constitutional mutation in a parent.<ref>[http://www.daisyfund.org/rb/about/genetics.html RB1 Genetics] at Daisy's Eye Cancer Fund. Retrieved May 2011</ref>
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A '''germline mutation''' is a form of [[mutation]] and is any detectable and heritable variation in the lineage of [[germ cell]]s. [[Mutation]]s in these cells are transmitted to [[offspring]], while, on the other hand, those in [[somatic]] cells are not. A germline mutation gives rise to a '''constitutional mutation''' in the offspring, that is, a mutation that is present in virtually every cell. A constitutional mutation can also occur very soon after [[fertilisation]], or continue from a previous constitutional mutation in a parent.<ref>[http://www.daisyfund.org/rb/about/genetics.html RB1 Genetics] at Daisy's Eye Cancer Fund. Retrieved May 2011</ref>
 
This distinction is most important in [[animal]]s, where germ cells are distinct from somatic cells. However, in [[plant]]s, the reproductive cells in a particular flower will be derived from the same [[meristem]] as the cells in that [[flower]] and on the [[Plant stem|stem]] leading to the flower, which is a different population of cells than those that give rise to the other flowers on the plant. [[Unicellular organism | Single-celled]] [[organism]]s have no distinction between germline and somatic tissues.
 
   
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This distinction is most important in [[animal]]s, where germ cells are distinct from somatic cells.
 
In animals, mutations are more likely to occur in [[sperm]] than in [[Ovum|ova]], because a larger number of cell divisions are involved in the production of sperm.<ref>[http://www.schizophreniaforum.org/for/curr/Malaspina/default.asp Schizophrenia Risk and the Paternal Germ Line]</ref>
 
In animals, mutations are more likely to occur in [[sperm]] than in [[Ovum|ova]], because a larger number of cell divisions are involved in the production of sperm.<ref>[http://www.schizophreniaforum.org/for/curr/Malaspina/default.asp Schizophrenia Risk and the Paternal Germ Line]</ref>
   

Latest revision as of 16:13, October 1, 2013

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A germline mutation is a form of mutation and is any detectable and heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring, while, on the other hand, those in somatic cells are not. A germline mutation gives rise to a constitutional mutation in the offspring, that is, a mutation that is present in virtually every cell. A constitutional mutation can also occur very soon after fertilisation, or continue from a previous constitutional mutation in a parent.[1]

This distinction is most important in animals, where germ cells are distinct from somatic cells. In animals, mutations are more likely to occur in sperm than in ova, because a larger number of cell divisions are involved in the production of sperm.[2]

Mutations that are not germline are somatic mutations, which are also called acquired mutations.

See also Edit

References Edit

  1. RB1 Genetics at Daisy's Eye Cancer Fund. Retrieved May 2011
  2. Schizophrenia Risk and the Paternal Germ Line
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