Ad blocker interference detected!
Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers
Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.
- Acknowledge prior contact and receipt of family history information
- Assess the most important concerns since there are so many issues at hand
- Discuss family plans (timing, size, etc.) and how those plans may be influenced by what is learned today
Intake and Family HistoryEdit
- Review family history information and personal health information already obtained
- Use pedigree to make the review easier
- Specifically ask about cancer in the family
- Ask about pituitary tumor
- When was it diagnosed? How? By whom?
- What symptoms was she having?
- Did she receive any treatment beside the drug mentioned?
- Was surgery or radiation therapy ever discussed?
- Has her physician discussed recurrence risks with her?
What is the Pituitary Gland?Edit
- The pituitary gland is a small, bean-shaped gland located in the center of the brain just above the back of the nose
- The pituitary gland makes hormones that affect the growth and functions of other glands in the body; therefore it is sometimes called the "master gland"
- Some hormones produced by the pituitary include: Thyroid Stimulating Hormone, Growth Hormone, Adrenocorticotropic Hormone, Luteinizing and Follicle Stimulating Hormones, Vasopressin, and others
- When there is an abnormality of the pituitary gland, it often produces either too much or too little of one or a combination of hormones. This can result in a variety of hormonal problems that can affect the whole body.
- Enlargement of the gland can also cause visual disturbances and/or impairment
- Pituitary tumors or adenomas are almost always benign which means that they grow slowly and do not spread to other parts of the body
- Pituitary tumors are rare.
- Some may be "silent" lesions that are incidentally found at autopsy
- The manifestations of a pituitary tumor depend on the hormones secreted by the tumor and the pattern of growth
- Some hormonally active tumors are those that produce adrenocorticotropic hormone (ACTH), prolactin, or growth-hormone
- Hormonally-inactive adenomas are often larger and may exhibit invasive properties. Thus, the likelihood for blindness is greater in patients with this tumor type
- Pituitary tumors are seen in one of the multiple endocrine neoplasia (MEN) syndromes. MEN type I is well recognized, dominantly inherited, and comprises tumors of the parathyroid, pancreas and pituitary. Eighty percent of patients have involvement of 2 or more glands, and pituitary tumors occur in 54% to 80% of patients with MEN I.
- MRI most readily determines the presence of a pituitary tumor, although it may also be established by CT (computer tomography) scan.
- Many patients experience visual loss. Headaches occur in about 20%.
- Treatment depends upon the type of tumor and if it extends into the brain around the pituitary.
- Hormone-secreting tumors may be treated with surgery or radiation therapy. Drug therapy with bromocriptine has been used with success in patients with prolactin-secreting tumors.
- Lesions that extend beyond the confines of the pituitary often require radiation therapy and surgery
- I could not find a population rate for pituitary tumors, only that they are "very rare"
- sister was probably treated with bromocriptine which was used in the past for lactation cessation and is currently used to treat prolactin-secreting pituitary tumors
- Her tumor was likely small at the start, and she has responded well to treatment thus far
- Even if sister has a recurrence of the tumor, it will not affect the risk that this couple would have a child with a pituitary tumor
- Buckman, Robert. What you Really Need to Know about Cancer, p61.
- CancerNet (A service of the NCI) online database
- DeVita, Vincent T., Samuel Hellman, and Steven A. Rosenbert. Cancer: Principles & Practice of Oncology. Volume 2: pp1725, 2066-2068
- Genetics in Clinical Oncology, pp108-109.
- Pituitary Network Association (PNA) website
The information in this outline was last updated in 2002.