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Individual differences |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |
What is Ewing's sarcoma/PNET?Edit
- a cancer that can start in bone or soft tissues
- most common sites for are the pelvis, the thigh, and the trunk of the body
- peak ages are 10-20, but younger children and older adults can also get it
- half are under 15 years
- less common before 5 or after 30
- no known cause
- cells in the tumours have a piece of chromosome 11 moved to chromosome 22
- 85% contain chromosomal translocation at the t(11;22)(q24;q12)
- the genetic change occurs only in the tumour cells, not in the sperm or egg
- 2.5% of cases of childhood cancer
- development of the tumour appears to be in some way related to periods in life with rapid growth, hence the average for tumour development is 14-15 years
- slightly more common in boys than in girls
- most common early signs are pain and swelling
- can spread to other parts of the body
- always requires treatment to the whole body (chemotherapy, surgery, radiation therapy)
- vary from person to person depending on the location and size of the cancer
- most common symptoms are pain and swelling or tenderness in the affected area
- pain may become very intense when the tumour is located near important nerves, like in the sacrum, pelvis or spine
- swelling is often seen, especially when the log bones of the arms or legs are affected
- tiredness, fever, weight loss, and anaemia
The information in this outline was last updated in 2002.
This material has been imported fom the wikibook "Genetic counseling"[ http://en.wikibooks.org/wiki/Genetic_counseling] under the GNU Free Documentation License.