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(New page: {{BioPsy}} {{protein | Name = galanin receptor 1 | caption = | image = | width = | HGNCid = 4132 | Symbol = GALR1 | AltSymbols = GALNR1, GALNR | EntrezGene = 2587 | OMIM = 600377 | ...)
 
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So far three subtypes are known to exist: [[galanin receptor 1|GAL-R1]], [[galanin receptor 2|GAL-R2]], and [[galanin receptor 3|GAL-R3]].<ref name="pmid10689365">{{cite journal | author = Branchek TA, Smith KE, Gerald C, Walker MW | title = Galanin receptor subtypes | journal = Trends Pharmacol. Sci. | volume = 21 | issue = 3 | pages = 109–17 | year = 2000 | pmid = 10689365 | doi = 10.1016/S0165-6147(00)01446-2 }}</ref> The specific function of each subtype remains to be fully elucidated, although great progress is currently being made in this respect with the generation of receptor subtype-specific knockout mice.
 
So far three subtypes are known to exist: [[galanin receptor 1|GAL-R1]], [[galanin receptor 2|GAL-R2]], and [[galanin receptor 3|GAL-R3]].<ref name="pmid10689365">{{cite journal | author = Branchek TA, Smith KE, Gerald C, Walker MW | title = Galanin receptor subtypes | journal = Trends Pharmacol. Sci. | volume = 21 | issue = 3 | pages = 109–17 | year = 2000 | pmid = 10689365 | doi = 10.1016/S0165-6147(00)01446-2 }}</ref> The specific function of each subtype remains to be fully elucidated, although great progress is currently being made in this respect with the generation of receptor subtype-specific knockout mice.
   
Galanin receptors can be found throughout the peripheral and [[central nervous systems]] and the [[endocrine system]].
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Galanin receptors can be found throughout the peripheral and [[central nervous system]] and the [[endocrine system]].
   
 
==References==
 
==References==

Latest revision as of 09:09, March 5, 2009

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galanin receptor 1
Symbol(s): GALR1 GALNR1, GALNR
Locus: 18 q23
EC number [1]
EntrezGene 2587
OMIM 600377
RefSeq NM_001480
UniProt P47211
galanin receptor 2
Symbol(s): GALR2
Locus: 17 q25.3
EC number [2]
EntrezGene 8811
OMIM 603691
RefSeq NM_003857
UniProt O43603
galanin receptor 3
Symbol(s): GALR3
Locus: 22 q12.2 -13.1
EC number [3]
EntrezGene 8484
OMIM 603692
RefSeq NM_003614
UniProt O60755

The galanin receptor is a G protein-coupled receptor, or metabotropic receptor which binds galanin.[1]

So far three subtypes are known to exist: GAL-R1, GAL-R2, and GAL-R3.[2] The specific function of each subtype remains to be fully elucidated, although great progress is currently being made in this respect with the generation of receptor subtype-specific knockout mice.

Galanin receptors can be found throughout the peripheral and central nervous system and the endocrine system.

ReferencesEdit

  1. Lang R, Gundlach AL, Kofler B (2007). The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease. Pharmacol. Ther. 115 (2): 177–207.
  2. Branchek TA, Smith KE, Gerald C, Walker MW (2000). Galanin receptor subtypes. Trends Pharmacol. Sci. 21 (3): 109–17.

External linksEdit



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