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Frontonasal prominence

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During the third week of embryonic development, two areas of thickened ectoderm, the olfactory areas, appear immediately under the fore-brain in the anterior wall of the stomodeum, one on either side of a region termed the frontonasal prominence (or process).

By the upgrowth of the surrounding parts these areas are converted into pits, the olfactory pits, which indent the frontonasal prominence and divide it into a medial and two lateral nasal processes.

There is some evidence that development involves Sonic hedgehog and Fibroblast growth factor 8.[1]

ReferencesEdit

  1. Abzhanov A, Cordero DR, Sen J, Tabin CJ, Helms JA (December 2007). Cross-regulatory interactions between Fgf8 and Shh in the avian frontonasal prominence. Congenit Anom (Kyoto) 47 (4): 136–48.

External linksEdit

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.

Template:Embryology of head and neck

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