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Fluspirilene

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Fluspirilene chemical structure
Fluspirilene

8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
IUPAC name
CAS number
1841-19-6
ATC code

N05AG01

PubChem
3396
DrugBank
[1]
Chemical formula {{{chemical_formula}}}
Molecular weight 475.573
Bioavailability
Metabolism
Elimination half-life
Excretion
Pregnancy category
Legal status
Routes of administration IM

Fluspirilene is a diphenylbutylpiperidine antipsychotic drug, used for the treatment of schizophrenia. It is administered intramuscularly.

It was discovered at Janssen Pharmaceutica in 1963.

ReferencesEdit

  • van Epen JH, Experience with fluspirilene (R 6218), a long-acting neuroleptic, Psychiatr Neurol Neurochir. 1970 Jul-Aug;73(4):277-84.
  • Janssen PA, Niemegeers CJ, Schellekens KH, Lenaerts FM, Verbruggen FJ, van Nueten JM, Marsboom RH, Herin VV, Schaper WK., The pharmacology of fluspirilene (R 6218), a potent, long-acting and injectable neuroleptic drug, Arzneimittelforschung. 1970 Nov;20(11):1689-98.

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