Fluspirilene
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Fluspirilene chemical structure | |
| 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one IUPAC name | |
| CAS number 1841-19-6 | ATC code |
| PubChem 3396 | DrugBank [1] |
| Chemical formula | {{{chemical_formula}}} |
| Molecular weight | 475.573 |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Pregnancy category | |
| Legal status | |
| Routes of administration | IM |
Fluspirilene is a diphenylbutylpiperidine antipsychotic drug, used for the treatment of schizophrenia. It is administered intramuscularly.
It was discovered at Janssen Pharmaceutica in 1963.
References
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- van Epen JH, Experience with fluspirilene (R 6218), a long-acting neuroleptic, Psychiatr Neurol Neurochir. 1970 Jul-Aug;73(4):277-84.
- Janssen PA, Niemegeers CJ, Schellekens KH, Lenaerts FM, Verbruggen FJ, van Nueten JM, Marsboom RH, Herin VV, Schaper WK., The pharmacology of fluspirilene (R 6218), a potent, long-acting and injectable neuroleptic drug, Arzneimittelforschung. 1970 Nov;20(11):1689-98.
