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Flupentixol

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Flupenthixol
Flupentixol

2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene] propyl]piperazin-1-yl]ethanol
IUPAC name
CAS number
2709-56-0
ATC code

N05AF01

PubChem
17012
DrugBank
APRD00388
Chemical formula {{{chemical_formula}}}
Molecular weight 434.519 g/mol
Bioavailability
Metabolism
Elimination half-life 19 to 39 hours
Excretion {{{excretion}}}
Pregnancy category
Legal status Rx-only
Routes of administration Oral


A typical antipsychotic (previously known as major tranquilizers)

Mode of action:
Specifically antagonizes D1 and D2 dopamine receptors (as well as serotonin).

The typical antipsychotics are less used now that the atypical antipsychotics are available (with less side effects) but the Flupenthixol decanoate ester is useful in patients who are likely to be non-compliant - it is given as an intramuscular depot injection lasting up to 4 weeks from a single injection.




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