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Ethanolamine-O-sulfate
Ethanolamine-O-sulfate
General
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Chiral rotation [α]D
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Except where noted otherwise, data are given for
materials in their standard state (at 25 °C, 100 kPa)
Infobox disclaimer and references


Ethanolamine-O-sulfate (EOS) is an ester of sulfuric acid and ethanolamine. EOS is a GABA transaminase inhibitor which prevents the metabolism of GABA.[1] It is used as a biochemical tool in studies involving GABA.

EOS is also a diuretic[2] and an anticonvulsant.[3]

See also[]

References[]

  1. Gudelsky G A; Apud J A; Masotto C; Locatelli V; Cocchi D; Racagni G; Muller E E (1983). Ethanolamine-O-sulfate enhances gamma-aminobutyric acid secretion into hypophysial portal blood and lowers serum prolactin concentrations. Neuroendocrinology 37 (5): 397–9.
  2. German Patent DE2345291: Diuretic aminoalkyl sulfates; Somani, Pitambar; Martin, Donald Lyons (1974)
  3. Anlezark, Gill; Horton, Roger W.; Meldrum, Brian S.; Sawaya, M. Christina B. (1976). Anticonvulsant action of ethanolamine-O-sulfate and di-n-propylacetate and the metabolism of γ-aminobutyric acid (GABA) in mice with audiogenic seizures. Biochemical Pharmacology 25 (4): 413–417.
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