(Redirecting to Dopamine agonist) |
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| + | [[Image:Dopamine2.svg|thumb||[[Dopamine]]]] |
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| + | A '''dopamine agonist''' is a compound that activates [[dopamine receptor]]s, mimicking the effect of the neurotransmitter [[dopamine]]. |
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| + | ==Uses== |
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| + | Some medical [[drug]]s act as dopamine agonists; they are typically used for treating [[Parkinson's disease]] and certain pituitary tumors (prolactinomas), and may be useful for [[restless legs syndrome]] (RLS). Both [[Requip]] ([[Ropinirole]]) and [[Mirapex]] ([[Pramipexole]]) are FDA approved for the treatment of RLS. |
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| + | There is also an ongoing clinical trial to test the effectiveness of [[Requip]] ([[ropinirole]]), a '''dopamine agonist''', in reversing the symptoms of [[SSRI]] induced [[sexual dysfunction]]. <ref>{{ClinicalTrialsGov|NCT00334048}} - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"</ref> |
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| + | ==Examples== |
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| + | Examples of '''dopamine agonists''' include: |
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| + | * Parlodel ([[bromocriptine]]) |
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| + | * Dostinex ([[cabergoline]]) |
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| + | * Permax ([[pergolide]]) - Removed from market March 29,2007.<ref>[http://www.fda.gov/bbs/topics/NEWS/2007/NEW01596.html FDA Announces Voluntary Withdrawal of Pergolide Products<!-- Bot generated title -->]</ref> |
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| + | * Mirapex ([[pramipexole]]) |
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| + | * Requip ([[ropinirole]]) |
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| + | * Apokyn ([[apomorphine]]) |
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| + | * Neupro ([[rotigotine]]) |
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| + | == See also == |
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| + | * [[Agonist]] |
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| + | * [[Amphetamine]] |
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| + | * [[Apomorphine]] |
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| + | * [[Morphine]] |
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| + | * [[Quinpirole]] |
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| + | ==References== |
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| + | <references/> |
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| + | ==External links== |
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| + | * {{MeshName|Dopamine+Agonists}} |
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| + | {{Dopamine agonists}} |
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| + | {{Receptor agonists and antagonists}} |
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| + | [[Category:Dopamine agonists|*]] |
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| + | [[Category:Drugs]] |
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Latest revision as of 18:12, 11 February 2008
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A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.
Uses
Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson's disease and certain pituitary tumors (prolactinomas), and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.
There is also an ongoing clinical trial to test the effectiveness of Requip (ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. [1]
Examples
Examples of dopamine agonists include:
- Parlodel (bromocriptine)
- Dostinex (cabergoline)
- Permax (pergolide) - Removed from market March 29,2007.[2]
- Mirapex (pramipexole)
- Requip (ropinirole)
- Apokyn (apomorphine)
- Neupro (rotigotine)
See also
References
- ↑ ClinicalTrials.gov NCT00334048 - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"
- ↑ FDA Announces Voluntary Withdrawal of Pergolide Products
External links
Anti-parkinson drugs: dopaminergic agents (N04B) | |
|---|---|
| Dopa and derivatives |
Levodopa, Melevodopa, Etilevodopa |
| Adamantane derivatives | |
| Dopamine agonists |
Apomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958 |
| MAOIs | |
| Other |
Tolcapone, Entacapone, Budipine |
| This page uses Creative Commons Licensed content from Wikipedia (view authors). |