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A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.

Contents 1 Uses 2 Examples 3 See also 4 References 5 External links

[edit] Uses

Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson's disease and certain pituitary tumors (prolactinomas), and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.

There is also an ongoing clinical trial to test the effectiveness of Requip (ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. ^[1]

[edit] Examples

Examples of dopamine agonists include:

• Parlodel (bromocriptine)
• Dostinex (cabergoline)
• Permax (pergolide) - Removed from market March 29,2007.^[2]

• Mirapex (pramipexole)
• Requip (ropinirole)
• Apokyn (apomorphine)
• Neupro (rotigotine)

[edit] See also

• Agonist
• Amphetamine
• Apomorphine
• Morphine
• Quinpirole

[edit] References

1. ↑ ClinicalTrials.gov NCT00334048 - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"
2. ↑ FDA Announces Voluntary Withdrawal of Pergolide Products

[edit] External links

• MeSH Dopamine+Agonists

v·d·e Anti-parkinson drugs: dopaminergic agents (N04B)
Dopa and derivatives	Levodopa, Melevodopa, Etilevodopa
Adamantane derivatives	Amantadine
Dopamine agonists	Apomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958
MAOIs	Selegiline, Rasagiline
Other	Tolcapone, Entacapone, Budipine

v·d·e Receptor agonists, antagonists, and reuptake inhibitors
Dopamine receptor	Dopamine agonist • Dopamine antagonist • Dopamine reuptake inhibitor
5-HT (serotonin) receptor	Serotonin receptor agonist • Serotonin antagonist (5-HT3) • Serotonin uptake inhibitor (SSRI)
Adrenergic receptor	Adrenergic agonist (Alpha, Beta2) • Adrenergic antagonist (Alpha, Beta) • Adrenergic uptake inhibitor
Acetylcholine receptor	Cholinergic (Muscarinic, Nicotinic) • Anticholinergic (Muscarinic, Nicotinic) • Acetylcholinesterase inhibitor
Histamine receptor	Histamine agonist • Histamine antagonist (H1, H2)
GABA receptor	GABA agonist • GABA antagonist
NMDA receptor	NMDA receptor antagonist

This page uses content from the English-language version of Wikipedia. The original article was at Dopamine agonist. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.