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Clinical depression - Serotonin

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  • Caspi, A.; Sugden, K.; Moffitt, T. E.; Taylor, A.; Craig, I. W.; Harrington, H.; McClay, J.; Mill, J.; Martin, J.; Braithwaite, A.; Poulton, R. (2003). Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301: 386-389, PubMed ID : 12869766
  • Hoefgen, B.; Schulze, T. G.; Ohlraun, S.; von Widdern, O.; Hofels, S.; Gross, M.; Heidmann, V.; Kovalenko, S.; Eckermann, A.; Kolsch, H.; Metten, M.; Zobel, A.; Becker, T.; Nothen, M. M.; Propping, P.; Heun, R.; Maier, W.; Rietschel, M. (2005). The power of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder. Biol. Psychiat. 57: 247-251, PubMed ID : 15691525
  • Murphy, G. M., Jr.; Hollander, S. B.; Rodrigues, H. E.; Kremer, C.; Schatzberg, A. F. (2004). Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression. Arch. Gen. Psychiat. 61: 1163-1169, PubMed ID : 15520364
  • Ogilvie, A. D.; Battersby, S.; Bubb, V. J.; Fink, G.; Harmar, A. J.; Goodwin, G. M.; Smith, C. A. D. (1996). Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet 347: 731-733, PubMed ID : 8602004
  • Pezawas, L.; Meyer-Lindenberg, A.; Drabant, E. M.; Verchinski, B. A.; Munoz, K. E.; Kolachana, B. S.; Egan, M. F.; Mattay, V. S.; Hariri, A. R.; Weinberger, D. R. (2005). 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nature Neurosci. 8: 828-834, PubMed ID : 15880108
  • Smits, K. M.; Smits, L. J. M.; Schouten, J. S. A. G.; Stelma, F. F.; Nelemans, P.; Prins, M. H. (2004). Influence of SERTPR and STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review. Molec. Psychiat. 9: 433-441.
  • Taylor, W. D.; Steffens, D. C.; Payne, M. E.; MacFall, J. R.; Marchuk, D. A.; Svenson, I. K.; Krishnan, K. R. R. (2005).Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression. Arch. Gen. Psychiat. 62: 537-544,PubMed ID : 15867107
  • Yu, Y. W.-Y.; Tsai, S.-J.; Chen, T.-J.; Lin, C.-H.; Hong, C.-J. (2002)

Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders. Molec. Psychiat. 7: 1115-1119.


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