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Depression - Suicide by antidepressant

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Overdoses of antidepressants are used as a means of suicide and are a source of accidental death.



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  • Cipriani, A. (2005). Forensic database study suggests selective serotonin reuptake inhibitors do not increase the risk of suicide in people taking antidepressants. Evid. Based Ment. Health 8: 113-113 [Full text]
  • Committee on Safety of Medicines, Medicines and Healthcare products Regulatory Agency. CSM expert working group on safety of selective serotonin reuptake inhibitors. Suicidal thoughts/behaviour. www.mhra.gov.uk/news/2004/SSRIs_SPC.pdf Full text
  • Healy D. Lines of evidence on the risks of suicide with selective sertonin reuptake inhibitors. Psychother Psychosomat 2003;72: 71-9.
  • Isacsson, G., Holmgren, P., Druid, H., & Bergman, U. (1997). The utilization of antidepressants: A key issue in the prevention of suicide: An analysis of 5281 suicides in Sweden during the period 1992-1994. Acta Psychiatrica Scandinavica, 96, 94-100.
  • National Institute for Clinical Excellence. Depression: management of depression in primary and secondary care. Clinical Guideline 23. London: NICE, 2004. www.nice.org.uk/pdf/CG023quickrefguide.pdf
  • Montgomery, S.A. (1997). Suicide and antidepressants. Annals of the New York Academy of Sciences, 286, 329-336.

Oquendo, M.A., Malone, K.M., Ellis, S.P., Sackeim, H.A., & *Mann, J.J. (1999). Inadequacy of antidepressant treatment for patients with major depression who are at risk for suicidal behavior. American Journal of Psychiatry, 156, 190-194. van Praag HM. (2002)Why has the antidepressant era not shown a significant drop in suicide rates? Crisis23(2):77-82



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