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The Cys-loop ligand-gated ion channel superfamily is comprised of nicotinic acetylcholine, GABAA, GABAC, glycine and 5-HT3 receptors that are composed of five protein subunits and possess a characteristic loop formed by a disulphide bond between two cysteine residues.


  • Sine S, Engel A (2006). Recent advances in Cys-loop receptor structure and function.. Nature 440 (7083): 448-55. PMID 16554804.

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