Cys-loop receptors
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The Cys-loop ligand-gated ion channel superfamily is comprised of nicotinic acetylcholine, GABAA, GABAC, glycine and 5-HT3 receptors that are composed of five protein subunits and possess a characteristic loop formed by a disulphide bond between two cysteine residues.
References
Edit
- Sine S, Engel A (2006). Recent advances in Cys-loop receptor structure and function.. Nature 440 (7083): 448-55. PMID 16554804.
External linksEdit
Ion channel, receptor: ligand-gated ion channels | |
|---|---|
| Cys-loop receptors |
5-HT receptor (5-HT3 serotonin receptor (A)) - GABA receptor (GABA A (α1, α2, α3, α4, α5, α6, β1, β2, β3, γ2, γ3, ε), GABA C (ρ1, ρ2)) - Glycine receptor (α1, α2, β) - Nicotinic acetylcholine receptor (α1, α2, α3, α4, α5, α7, α9, β1, β2, β3, β4, δ, ε, (α4)2(β2)3, (α7)5, Ganglion type, Muscle type) |
| Ionotropic glutamate receptors |
AMPA (1, 2, 3, 4) - Kainate (1, 2, 3, 5) - NMDA (1, 2A, 2B, 2C, 2D) |
| ATP-gated channels | |
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