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Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage. They often lead to an increased tendency to develop certain types of malignancies.

The following chromosome instability syndromes are known:

• Ataxia telangiectasia
• Ataxia telangiectasia-like disorder
• Bloom syndrome
• Fanconi anaemia
• Nijmegen breakage syndrome

ReferencesEdit

• Taylor AM (2001). Chromosome instability syndromes. Best Pract Res Clin Haematol 14 (3): 631-44. PMID 11640873.