Chromosome 3 (human)

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)

Chromosome 3 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 3 spans almost 200 million base pairs (the building material of DNA) and represents about 6.5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 3 likely contains between 1,100 and 1,500 genes.

Genes

This list is incomplete; you can help by expanding it.

The following are some of the genes located on chromosome 3:

ALAS1: aminolevulinate, delta-, synthase 1
BTD: biotinidase
CCR5: chemokine (C-C motif) receptor 5
CPOX: coproporphyrinogen oxidase (coproporphyria, harderoporphyria)
HGD: homogentisate 1,2-dioxygenase (homogentisate oxidase)
MCCC1: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
MITF: microphthalmia-associated transcription factor
MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
PCCB: propionyl Coenzyme A carboxylase, beta polypeptide
PDCD10: programmed cell death 10
PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide
RAB7: RAB7, member RAS oncogene family
SCN5A: sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
SLC25A20: solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
TMIE: transmembrane inner ear
USH3A: Usher syndrome 3A
VHL: von Hippel-Lindau tumor suppressor
ZNF9: zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)

Diseases

This list is incomplete; you can help by expanding it.

The following diseases are some of those related to genes on chromosome 3:

alkaptonuria
biotinidase deficiency
Brugada syndrome
carnitine-acylcarnitine translocase deficiency
cerebral cavernous malformation
Charcot-Marie-Tooth disease
Charcot-Marie-Tooth disease, type 2
hereditary coproporphyria
hereditary nonpolyposis colorectal cancer
3-methylcrotonyl-CoA carboxylase deficiency
myotonic dystrophy
myotonic dystrophy, type 2
nonsyndromic deafness
nonsyndromic deafness, autosomal recessive
porphyria
propionic acidemia
Romano-Ward syndrome
Usher syndrome
Usher syndrome type III
von Hippel-Lindau syndrome
Waardenburg syndrome
Autism
Night blindness
Deafness
HIV infection, susceptibility/resistance to
Diabetes
Breast/colon/lung/pancreatic cancer
Usher syndrome/ Usher syndrome (Finland)
Ovarian cancer
Muir-Torre family cancer syndrome
Glaucoma, primary open angle
Essential tremors
Short stature
Leukoencephalopathy with vanishing white matter
Harderoporphyrinuria
Spinocerebellar ataxia
Moyamoya disease
Endplate acetlycholinesterase deficiency
Hypobetalipoproteinemia, familial
Septooptic dysplasia
Long QT syndrome
Cataracts
Mucopolysaccharidosis
Heart block, progressive/nonprogressive
Malignant hyperthermia susceptibility
Atransferrinemia
Sucrose intolerance
Cerebral cavernous malformations
Neuropathy, hereditary motor and sensory, Okinawa type
Protein S deficiency
T-cell leukemia translocation altered gene
Xeroderma pigmentosum, complementation group c
Hailey-Hailey disease
Coproporphyria
Dopamine receptor
Glycogen storage disease
Arrhythmogenic right ventricular dysplasia
Pseudo-Zellweger syndrome
Blepharophimosis, epicanthus inversus and ptosis type 1
Lymphomas
Metaphyseal chondrodysplasia, Murk Jansen type
Moebius syndrome
Epidermolysis bullosa

Chromosome 3 (human)

Genes

Diseases

See also

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