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Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)
choline acetyltransferase | |
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Symbol(s): | CHAT |
Locus: | 10 q11.2 |
EC number | 2.3.1.6 |
EntrezGene | 1103 |
OMIM | 118490 |
RefSeq | NM_020549 |
UniProt | P28329 |
Choline acetyltransferase (EC 2.3.1.6) is an enzyme which is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. It joins Acetyl CoA to choline, resulting in the formation of the neurotransmitter acetylcholine.
It is often used as a marker, immunohistochemically, for motor neurons (motoneurons).
See also[]
- Acetyltransferase
External links[]
Transferases: acyltransferases (EC 2.3) | |
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2.3.1: other than amino-acyl groups (mostly acetyltransferases) |
N-Acetylglutamate synthase - Choline acetyltransferase - Acetyl-Coenzyme A acetyltransferase - Dihydrolipoyl transacetylase - Acetyl-CoA C-acyltransferase - Beta-galactoside transacetylase - Carnitine O-palmitoyltransferase (CPT1, CPT2) - Acyltransferase like 2 - Chloramphenicol acetyltransferase - Aminolevulinic acid synthase - Beta-ketoacyl-ACP synthase - Glyceronephosphate O-acyltransferase - Lecithin-cholesterol acyltransferase - Histone acetyltransferase (P300/CBP) - Serotonin N-acetyl transferase |
2.3.2 - Aminoacyltransferases |
Gamma glutamyl transpeptidase - Peptidyl transferase - Transglutaminase (Tissue transglutaminase, Keratinocyte transglutaminase, Factor XIII) |
2.3.3 - converted into alkyl on transfer |
Citrate synthase - ATP citrate lyase - HMG-CoA synthase |
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