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- Main article: Amines
| style="background: #F8EABA; text-align: center;" colspan="2" | Chlorisondamine |
|---|---|
| 200px | |
| 4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-(2-(trimethylammonio)ethyl)-1H-isoindolium dichloride | |
| Identifiers | |
| CAS number | 7701-62-4 |
| PubChem | 6243 |
| SMILES | ClC1=C2C(C[N](C)(CC[N](C)(C)C)C2)=C(Cl)C(Cl)=C1Cl.[Cl-].[Cl-] |
| Properties | |
| Molecular formula | C14H20Cl6N2 |
| Molar mass | 429.04 g mol-1 |
| Hazards | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Chlorisondamine is a nicotinic antagonist that produces both ganglionic and central blockades. Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin and other associated glycolipids.[1][2][3]
References
Edit
- ↑ Woods, A. S.; Moyer, S. C.; Wang, H. Y. J.; Wise, R. A., Interaction of chlorisondamine with the neuronal nicotinic acetylcholine receptor. Journal of Proteome Research 2003, 2 (2), 207-212.
- ↑ Jackson, S. N.; Wang, H. Y. J.; Woods, A. S., Direct tissue analysis of phospholipids in rat brain using MALDI-TOFMS and MALDI-ion mobility-TOFMS. Journal of the American Society for Mass Spectrometry 2005, 16 (2), 133-138.
- ↑ Woods, A. S.; Ugarov, M.; Egan, T.; Koomen, J.; Gillig, K. J.; Fuhrer, K.; Gonin, M.; Schultz, J. A., Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS. Analytical Chemistry 2004, 76 (8), 2187-2195.
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