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Chloride channel

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Chloride channels are a superfamily of poorly understood ion channels consisting of approximately 13 members.

Chloride channels are important for setting cell resting membrane potential and maintaining proper cell volume. These channels conduct Cl- as well as other anions such as HCO3-, I-, SCN-, and NO3-. The structure of these channels is also not other known channels. Chloride channel subunits contain between 1 and 12 transmembrane segments. Some members of this family are activated by voltage, while others are activated by Ca2+, extracellular ligands, and pH among other modulators.[1]

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ReferencesEdit

    1. Suzuki M., Morita T. and Iwamoto, T. (2006) Diversity of Cl(-) channels. Cell Mol Life Sci. 63(1):12-24. Entrez PubMed 16314923
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