Chloride channel

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Chloride channels are a superfamily of poorly understood ion channels consisting of approximately 13 members.

Chloride channels are important for setting cell resting membrane potential and maintaining proper cell volume. These channels conduct Cl^- as well as other anions such as HCO₃^-, I^-, SCN^-, and NO₃^-. The structure of these channels is also not other known channels. Chloride channel subunits contain between 1 and 12 transmembrane segments. Some members of this family are activated by voltage, while others are activated by Ca²⁺, extracellular ligands, and pH among other modulators.^[1]

Contents 1 Genes 2 See also 3 External links 4 References

[edit] Genes

• CLCN1, CLCN2, CLCN3, CLCN4, CLCN5, CLCN6, CLCN7
• CLCNKA, CLCNKB
• CLIC1, CLIC2, CLIC3, CLIC4, CLIC5, CLIC6
• CLNS1A, CLNS1B
• CLCA1, CLCA2, CLCA3, CLCA4

[edit] See also

• Cystic fibrosis transmembrane conductance regulator
• Thomsen disease

[edit] External links

• MeSH Chloride+channels

[edit] References

• 1. ↑ Suzuki M., Morita T. and Iwamoto, T. (2006) Diversity of Cl(-) channels. Cell Mol Life Sci. 63(1):12-24. Entrez PubMed 16314923

This page uses content from the English-language version of Wikipedia. The original article was at Chloride channel. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.