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Charles Zuker

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Charles S. Zuker
Born 1957
Citizenship USA
Nationality Chile
Fields Neuroscience
Institutions UC San Diego 1987-2009, Columbia University 2009-present
Alma mater MIT
Doctoral advisor Harvey Lodish

Charles S. Zuker is an American molecular geneticist and neurobiologist of Chilean descent.

Education and trainingEdit

Zuker attended the Universidad Catolica de Valparaiso in Chile, and obtained his Ph.D. from MIT with Harvey Lodish. He did his postdoctoral studies at the University of California, Berkeley with Gerald Rubin.

Research interestEdit

TasteEdit

His lab has contributed to our understanding of mammalian taste, in collaboration with Nicholas Ryba's laboratory at the NIH beginning in the 1990s.

Danielle Reed studies on the genetics of bitter taste perception led to identification of a critical region of human Chromosome 5p15 whose variation correlated with a person's ability to taste the bitterness of PROP (propylthiouracil). This finding ultimately led to the discovery by Adler and co-workers (including Charles Zuker) of a family of bitter taste receptors (taste receptor) located within this critical region of the chromosome.

Prior to working on mammalian taste, his lab focused on visual signal transduction pathways in Drosophila melanogaster (fruit fly). He is an investigator of the Howard Hughes Medical Institute and a senior fellow at the Janelia Farm Research Campus. Zuker is a member of the United States National Academy of Sciences and the American Academy of Arts and Sciences. After more than 20 years at the University of California, San Diego, he began his appointment at Columbia University in 2009.


Further readingEdit

External linksEdit



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