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Channel blockers

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A channel blocker (CB) or ion channel blocker (ICB) is a type of drug which binds inside the pore of a specific type of ion channel and blocks the flow of ions through it, resulting in an alteration of the electrochemical gradient of the cell membrane of neurons and therefore a change in neurotransmission.

Types of Channel BlockersEdit

There are several different major classes of channel blockers, including:

The following types which act on ligand-gated ion channels (LGICs) via binding to their pore also exist:

These types of receptor antagonists are referred to as noncompetitive or uncompetitive.

See alsoEdit

ReferencesEdit

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