Centrophenoxine
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Centrophenoxine chemical structure | |
| IUPAC name | |
| CAS number 51-68-3 | ATC code [[ATC_code_|]][1] |
| PubChem 4039 | DrugBank [2] |
| Chemical formula | C12H16ClNO3 |
| Molecular weight | 257.713 |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Pregnancy category | |
| Legal status | |
| Routes of administration | |
Centrophenoxine (also called Meclofenoxate, and formerly sold under the brand name Lucidril®) is a drug used to treat the symptoms of senile dementia and Alzheimer's Disease. It is a compound of two biochemicals: dimethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA). DMAE is a natural substance, found especially in fish, and also produced in the human brain. pCPA is a synthetic compound that resembles to a variety of plant hormones called auxins.
Like DMAE, it is a precursor to the neurotransmitter acetylcholine and may increase levels of this chemical in the CNS. It is reported to improve memory and general cognition.
It is also used off-label as a nootropic, often combined with a racetam drug such as piracetam.
Side Effects & Contraindications
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Possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid Centrophenoxine. [1] Large doses may cause tight jaw clenching.
References
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1. Centrophenoxine Page @ The American Academy of Anti-Aging Medicine
External links
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- Collection of Scientific Abstracts on Centrophenoxine
- Brain Research and Information Network B.R.A.I.N.
- de:Centrophenoxin
- ru:Ацефен
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