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#redirect[[Anabolism]]
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{{BioPsy}}
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:''For the related metabolic process, see [[anabolism]].''
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'''Catabolism''' is the set of [[metabolic pathway]]s which break down molecules into smaller units and release [[energy]].<ref>{{cite web |url=http://www.chem.qmul.ac.uk/iupac/bioinorg/CD.html#8 |title=Glossary of Terms Used in Bioinorganic Chemistry: Catabolism |accessdate=2007-10-30 |last=de Bolster |first=M.W.G. |date=1997 |publisher=International Union of Pure and Applied Chemistry}}</ref> In catabolism, large molecules such as [[polysaccharide]]s, [[fatty acid]]s, [[nucleic acid]]s and [[protein]]s are broken down into smaller units such as [[monosaccharide]]s, [[fatty acid]]s, [[nucleotide]]s and [[amino acid]]s, respectively. As molecules such as polysaccharides, proteins and nucleic acids are made from long chains of these small [[monomer]] units, the large molecules are called [[polymer]]s.
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Cells use the [[monomers]] released from breaking down polymers to either construct new polymer molecules, or degrade the monomers further to simple waste products, releasing energy. Cellular wastes include [[lactic acid]], [[acetic acid]], [[carbon dioxide]], [[ammonia]], and [[urea]]. The creation of these wastes is usually an [[oxidation]] process involving a release of chemical free energy, some of which is lost as [[heat]], but the rest is used to drive the synthesis of [[adenosine triphosphate]] (ATP). This molecule acts as a way for the cell to transfer the energy released by catabolism to the energy-requiring reactions which make up [[anabolism]]. Catabolism therefore provides the chemical energy necessary for the maintenance and growth of cells. Examples of catabolic processes include [[glycolysis]], the [[citric acid cycle]], the breakdown of muscle protein in order to use amino acids as [[substrate (biochemistry)|substrate]]s for [[gluconeogenesis]] and breakdown of [[fat]] in [[adipose tissue]] to [[fatty acid]]s.
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There are many signals which control catabolism. Most of the known signals are [[hormone]]s and the molecules involved in metabolism itself. [[Endocrinologist]]s have traditionally classified many of the hormones as [[anabolic]] or catabolic, depending on which part of metabolism they stimulate. The "classic" catabolic hormones known since the early 20th century are [[cortisol]], [[glucagon]], and [[adrenaline]] (and other [[catecholamine]]s). In recent decades, many more hormones with at least some catabolic effects have been discovered, including [[cytokine]]s, [[orexin]] and [[hypocretin]] (a hormone pair), and [[melatonin]].
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== See also ==
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* [[Metabolism]]
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* [[Anabolism]]
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==References==
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{{reflist}}
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{{metabolism}}
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[[Category:Metabolism]]
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{{enWP|Catabolism]]

Latest revision as of 18:47, February 6, 2008

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For the related metabolic process, see anabolism.

Catabolism is the set of metabolic pathways which break down molecules into smaller units and release energy.[1] In catabolism, large molecules such as polysaccharides, fatty acids, nucleic acids and proteins are broken down into smaller units such as monosaccharides, fatty acids, nucleotides and amino acids, respectively. As molecules such as polysaccharides, proteins and nucleic acids are made from long chains of these small monomer units, the large molecules are called polymers.

Cells use the monomers released from breaking down polymers to either construct new polymer molecules, or degrade the monomers further to simple waste products, releasing energy. Cellular wastes include lactic acid, acetic acid, carbon dioxide, ammonia, and urea. The creation of these wastes is usually an oxidation process involving a release of chemical free energy, some of which is lost as heat, but the rest is used to drive the synthesis of adenosine triphosphate (ATP). This molecule acts as a way for the cell to transfer the energy released by catabolism to the energy-requiring reactions which make up anabolism. Catabolism therefore provides the chemical energy necessary for the maintenance and growth of cells. Examples of catabolic processes include glycolysis, the citric acid cycle, the breakdown of muscle protein in order to use amino acids as substrates for gluconeogenesis and breakdown of fat in adipose tissue to fatty acids.

There are many signals which control catabolism. Most of the known signals are hormones and the molecules involved in metabolism itself. Endocrinologists have traditionally classified many of the hormones as anabolic or catabolic, depending on which part of metabolism they stimulate. The "classic" catabolic hormones known since the early 20th century are cortisol, glucagon, and adrenaline (and other catecholamines). In recent decades, many more hormones with at least some catabolic effects have been discovered, including cytokines, orexin and hypocretin (a hormone pair), and melatonin.

See also Edit

ReferencesEdit

  1. de Bolster, M.W.G. Glossary of Terms Used in Bioinorganic Chemistry: Catabolism. International Union of Pure and Applied Chemistry. URL accessed on 2007-10-30.


Metabolism
Cell metabolism/Metabolism | Catabolism | Anabolism
Protein | Protein metabolism (Protein synthesis/Amino acid synthesis/Catabolism)
Carbohydrate | Carbohydrate metabolism (Anabolism/Catabolism)
Lipid | Lipid metabolism (Synthesis/Anabolism/Catabolism)
Metabolic pathway | Metabolic network
Cellular respiration (Anaerobic Aerobic)

{{enWP|Catabolism]]

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