CCK receptor
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| cholecystokinin A receptor | |
|---|---|
| Symbol(s): | CCKAR |
| Locus: | 4 p15.2 -p15.1 |
| EC number | [1] |
| EntrezGene | 886 |
| OMIM | 118444 |
| RefSeq | NM_000730 |
| UniProt | P32238 |
| cholecystokinin B receptor | |
|---|---|
| Symbol(s): | CCKBR |
| Locus: | 11 p15.4 |
| EC number | [2] |
| EntrezGene | 887 |
| OMIM | 118445 |
| RefSeq | NM_176875 |
| UniProt | P32239 |
Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors. There are two different subtypes CCK1 and CCK2. They are ~50% homologous. The CCK1 receptor binds mostly to Cholecystokinin while CCK2 also binds to gastrin. They are mostly involved in various digestive functions like gastrin-stimulated gastric acid secretion, gastric emptying and gut motility. In the brain, CCK functions as a neuropeptide and CCK receptors are involved in nociception, anxiety, memory and hunger.
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| This page uses content from the English-language version of Wikipedia. The original article was at CCK receptor. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License. |
