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The Bezold–Jarisch reflex involves a variety of cardiovascular and neurological processes which cause hypopnea (overly shallow breathing or an abnormally low respiratory rate) and bradycardia (abnormally low resting heart rate).
Prolonged upright posture results in some degree of pooling of blood in the lower extremities that can lead to diminished intracardiac volume.
This phenomenon is accentuated if the individual is dehydrated.
It usually occurs in nitrate therapy and use of serotonin agonists.
Nervous system physiology: neurophysiology - reflex
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