Psychology Wiki


34,203pages on
this wiki
Add New Page
Talk0 Share

Benperidol chemical structure

1-[1-[4-(4-fluorophenyl)-4-oxo-butyl] -4-piperidyl]-3H-benzoimidazol-2-one
IUPAC name
CAS number
ATC code


Chemical formula {{{chemical_formula}}}
Molecular weight 381.443g/mol
Elimination half-life
Pregnancy category
Legal status
Routes of administration Oral

Benperidol is a drug which is a highly potent butyrophenone derivative. It is in fact the most potent neuroleptic on the european market, with chlorpromazine equivalency as high as 75 to 100 (about 150 to 200% potency in terms of dose compared to haloperidol).[1]. It is an antipsychotic, which can be used for the treatment of schizophrenia[2], but it is primarily used to control deviant, antisocial hypersexual behaviour[3], and is sometimes prescribed to sex offenders as a condition of their parole, as an alternative to anti-androgen drugs such as cyproterone.[4]

Benperidol was discovered at Janssen Pharmaceutica in 1961.

References Edit

  1. Möller; Müller; Bandelow: Neuroleptika, 2001, WVG; ISBN 3-8047-1773-X (in German)
  2. Bobon J, Collard J, Lecoq R, Benperidol and promazine: a "double blind" comparative study in mental geriatrics, Acta Neurol Belg. 1963 Oct;63:839-43.
  3. British National Formulary (49th), British Medical Association 2005 p 183
  4. Murray MA, Bancroft JH, Anderson DC, Tennent TG, Carr PJ., Endocrine changes in male sexual deviants after treatment with anti-androgens, oestrogens or tranquillizers, Journal of Endocrinology. 1975 Nov;67(2):179-88.

Ad blocker interference detected!

Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.

Also on Fandom

Random Wiki