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Benactyzine

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Benactyzine chemical structure
Benactyzine

2-diethylaminoethyl 2-hydroxy-2,2-di(phenyl)acetate
IUPAC name
CAS number
302-40-9
ATC code

[[ATC_code_|]][1]

PubChem
9330
DrugBank
[2]
Chemical formula {{{chemical_formula}}}
Molecular weight 327.42 g/mol
Bioavailability
Metabolism
Elimination half-life
Excretion
Pregnancy category
Legal status
Routes of administration


Benactyzine is an anticholinergic drug. It is a glycolic acid ester, related to other drugs such as the piperidinyl benzilates and 3-Quinuclidinyl benzilate but with much less potent anticholinergic effects.

Benactyzine has been used as an antidepressant,[1] however its use for this application is limited by anticholinergic side effects such as dry mouth and nausea, and at high doses it can cause more severe symptoms such as deliriant and hallucinogenic effects. Consequently it is no longer widely used in medicine, although it is still a useful drug for scientific research.


See alsoEdit

References Edit

  1. McLaughlin B, Rickels K, Abidi M, Toro R. Meprobamate-benactyzine (Deprol) and placebo in two depressed outpatient populations. Psychosomatics. 1969 Mar-Apr;10(2):73-81.



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