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Chemical structure of L-aspartic acid | |
Aspartic acid | |
Systematic (IUPAC) name | |
(2S)-2-aminobutanedioic acid | |
Identifiers | |
PubChem | 5960 |
Chemical data | |
Formula | C4H7NO4 |
Mol. weight | 133.10 |
Complete data |
Aspartic acid (Asp, D), also known as aspartate, the name of its anion, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins.
As with each of the 20 natural amino acids, there are two abbreviations commonly used to designate aspartic acid: Asp (three letter) and D (one letter). The abbreviations signifying a choice of either aspartic acid or asparagine are Asx (three-letter) and B (one letter).[1]
As its name indicates, aspartic acid is the carboxylic acid analog of asparagine. It is non-essential in mammals, and might serve as an excitatory neurotransmitter in the brain. It is also a metabolite in the urea cycle, and participates in gluconeogenesis.
Action as a neurotransmitter
As a neurotransmitter, aspartic acid may provide resistance to fatigue and thus lead to endurance, although the evidence to support this idea is not strong.
References
IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. Nomenclature and Symbolism for Amino Acids and Peptides. Recommendations on Organic & Biochemical Nomenclature, Symbols & Terminology etc.. URL accessed on September 28, 2005.
See also
- Aspartate transaminase
- Sodium poly(aspartate), a synthetic polyamide
External links
Alanine | Arginine | Asparagine | Aspartic acid | Cysteine | Glutamic acid | Glutamine | Glycine | Histidine | Isoleucine | Leucine | Lysine | Methionine | Phenylalanine | Proline | Serine | Threonine | Tryptophan | Tyrosine | Valine |
Essential amino acid | Protein | Peptide | Genetic code |
bn:অ্যাস্পার্টিক অ্যাসিড ca:Àcid aspàrtic de:Asparaginsäure es:Ácido aspártico eo:Asparta acido fr:Acide aspartique id:Asam aspartat he:חומצה אספרטית lv:Aspargīnskābe lb:Aspartat lt:Asparto rūgštis nl:Asparaginezuur pt:Ácido aspártico ru:Аспарагиновая кислота fi:Asparagiinihappo sv:Asparaginsyra uk:Аспарагінова кислота zh:天冬氨酸
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