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(other Examples)
 
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==other Examples==
 
==other Examples==
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An '''antispasmodic''' (synonym: '''spasmolytic''') is a [[medication|drug]] or an herb that suppresses [[spasm]]s.<ref>{{eMedicineDictionary|Antispasmodic}}</ref><ref name="urlDorlands Medical Dictionary:antispasmodic">{{cite web |url=http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/one/000006336.htm#000006336 |title=Dorlands Medical Dictionary:antispasmodic |format= |work= |accessdate=}}</ref> These are usually caused by smooth [[muscle]] contraction, especially in tubular organs. The effect is to prevent [[spasms]] of the [[stomach]], [[intestine]] or [[urinary bladder]].
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==Examples==
 
Both [[dicyclomine]] and [[hyoscyamine]] are antispasmodic due to their [[anticholinergic]] action. Both of these drugs have general side effects and can worsen [[gastroesophageal reflux disease]].<ref>{{cite web |url=http://www.aafp.org/afp/20051215/2501.html |title=Treatment of Irritable Bowel Syndrome - December 15, 2005 -- American Family Physician |accessdate=2007-08-14 |format= |work=}}</ref>
 
Both [[dicyclomine]] and [[hyoscyamine]] are antispasmodic due to their [[anticholinergic]] action. Both of these drugs have general side effects and can worsen [[gastroesophageal reflux disease]].<ref>{{cite web |url=http://www.aafp.org/afp/20051215/2501.html |title=Treatment of Irritable Bowel Syndrome - December 15, 2005 -- American Family Physician |accessdate=2007-08-14 |format= |work=}}</ref>
   
[[Peppermint oil]] has been traditionally used as an antispasmodic, and a review of studies on the topic found that it "could be efficacious for symptom relief in [[irritable bowel syndrome|IBS]]"<ref name="pmid9672344">{{cite journal |author=Pittler MH, Ernst E |title=Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis |journal=Am. J. Gastroenterol. |volume=93 |issue=7 |pages=1131-5 |year=1998 |pmid=9672344 |doi=}}</ref> (as an antispasmodic) although more carefully controlled studies are needed. A later study showed it is an effective antispasmodic when test-applied topically to the intestine during [[endoscopy]].<ref name="pmid12665756">{{cite journal |author=Hiki N, Kurosaka H, Tatsutomi Y, ''et al'' |title=Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial |journal=Gastrointest. Endosc. |volume=57 |issue=4 |pages=475-82 |year=2003 |pmid=12665756 |doi=10.1067/mge.2003.156}}</ref>
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[[Mebeverine]], which is a muscolotropic spasmolytic with a strong and selective action on the smooth muscle spasm of the gastrointestinal tract, particularly of the colon. It does not have the anticholinergic side effect commonly seen in an anticholinergic antispasmodic.
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[[Peppermint oil]] has been traditionally used as an antispasmodic, and a review of studies on the topic found that it "could be efficacious for symptom relief in [[irritable bowel syndrome|IBS]]"<ref name="pmid9672344">{{cite journal |author=Pittler MH, Ernst E |title=Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis |journal=Am. J. Gastroenterol. |volume=93 |issue=7 |pages=1131–5 |year=1998 |pmid=9672344|doi=10.1111/j.1572-0241.1998.00343.x}}</ref> (as an antispasmodic) although more carefully controlled studies are needed. A later study showed it is an effective antispasmodic when test-applied topically to the intestine during [[endoscopy]].<ref name="pmid12665756">{{cite journal |author=Hiki N, Kurosaka H, Tatsutomi Y, ''et al.'' |title=Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial |journal=Gastrointest. Endosc. |volume=57 |issue=4 |pages=475–82 |year=2003 |pmid=12665756 |doi=10.1067/mge.2003.156}}</ref>
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The flower [[Liatris]], also called blazing star, has also been used as an antispasmodic{{Citation needed|date=November 2009}}. Another old common name for this plant is [[Colic Root]], alluding to its medicinal use as an antispasmodic for the [[intestines]].
   
The flower [[Liatris]], also called blazing star, has also been used as an antispasmodic. Another old common name for this plant is [[Colic Root]], alluding to its medicinal use as an antispasmodic for the [[intestines]].
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Most forms of the strain of Marijuana Indica are a highly effective anti spasm agent.{{Citation needed|date=November 2009}}
   
 
==See also==
 
==See also==

Latest revision as of 18:40, December 10, 2009

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For spasmolytics acting on skeletal muscle, see muscle relaxant.

An antispasmodic (synonym: spasmolytic) is a drug that suppresses smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.

These include:

other ExamplesEdit

An antispasmodic (synonym: spasmolytic) is a drug or an herb that suppresses spasms.[1][2] These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.

ExamplesEdit

Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. Both of these drugs have general side effects and can worsen gastroesophageal reflux disease.[3]

Mebeverine, which is a muscolotropic spasmolytic with a strong and selective action on the smooth muscle spasm of the gastrointestinal tract, particularly of the colon. It does not have the anticholinergic side effect commonly seen in an anticholinergic antispasmodic.

Peppermint oil has been traditionally used as an antispasmodic, and a review of studies on the topic found that it "could be efficacious for symptom relief in IBS"[4] (as an antispasmodic) although more carefully controlled studies are needed. A later study showed it is an effective antispasmodic when test-applied topically to the intestine during endoscopy.[5]

The flower Liatris, also called blazing star, has also been used as an antispasmodic[citation needed]. Another old common name for this plant is Colic Root, alluding to its medicinal use as an antispasmodic for the intestines.

Most forms of the strain of Marijuana Indica are a highly effective anti spasm agent.[citation needed]

See alsoEdit

ReferencesEdit

  1. Dictionary at eMedicine Antispasmodic
  2. Dorlands Medical Dictionary:antispasmodic.
  3. Treatment of Irritable Bowel Syndrome - December 15, 2005 -- American Family Physician. URL accessed on 2007-08-14.
  4. Pittler MH, Ernst E (1998). Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am. J. Gastroenterol. 93 (7): 1131–5.
  5. Hiki N, Kurosaka H, Tatsutomi Y, et al. (2003). Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial. Gastrointest. Endosc. 57 (4): 475–82.

External linksEdit


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