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Animal model refers to the induction in a non-human animal a disease, psychological or psychopathological process that is similar to a human condition. The use of model organisms allows researchers to investigate processes and disease states in ways which would be inaccessible in a human patient, performing procedures on the non-human animal that imply a level of harm that would not be considered ethical to inflict on a human.
In order to serve as a useful model, a modeled disease must be similar in etiology (mechanism of cause) and function to the human equivalent. Animal models are used to learn more about a disease, its diagnosis and its treatment. For instance, behavioral analogues of anxiety or pain in laboratory animals can be used to screen and test new drugs for the treatment of these conditions in humans.
The increase in knowledge of the genomes of non-human primates and other mammals that are genetically close to humans is allowing the production of genetically engineered animal tissues, organs and even animal species which express human diseases, providing a more robust model of human diseases in an animal model.
Research by problem
Research by animal
- Animal testing
- In vivo
- Model organism
- Animal testing on invertebrates
- Animal testing on rodents
- History of animal testing
- Experimental design
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Comparative:Animal models: Academic support materials
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