Wikia

Psychology Wiki

Amyloid beta

Talk0
34,136pages on
this wiki
Revision as of 15:13, April 11, 2006 by Lifeartist (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


Amyloid beta (Aβ or Abeta) is a protein fragment of 39-42 amino acids that is the main constituent of amyloid plaques in various neurological disorders, most prominently Alzheimer's disease.
APP processing

Processing of the amyloid precursor protein

Aβ is formed after sequential cleavage of the amyloid precursor protein (APP) by the β- and γ-secretases. APP is a transmembrane glycoprotein. Disregulation of APP metabolism — increasing either total Aβ levels or the relative concentration of the 42-amino acid form — seems to cause hereditary, early-onset Alzheimer's and is thought by many researchers to be involved in the etiology of the late-onset form.

External linkEdit


fi:Beta-amyloidi
This page uses Creative Commons Licensed content from Wikipedia (view authors).

Around Wikia's network

Random Wiki