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Adenosine diphosphate

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Adenosine diphosphate
Chemical name Adenosine 5'-(trihydrogen diphosphate)
Chemical formula C10H15N5O10P2
Molecular mass 427.20 g/mol
CAS number 58-64-0
SMILES O[C@H]1[C@H]([C@H](N2C3=C
(N=C2)C(N)=NC=N3)O[C@@H]
1COP(O)(OP(O)(O)=O)=O)O
ADP chemical structure

Adenosine diphosphate, abbreviated ADP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleotide adenine. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine.

ADP is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells.

ADP is stored in platelet dense granules and is released upon platelet activation. ADP interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12 and P2X1), leading to further platelet activation.[1] ADP in the blood is converted to adenosine by the action of ecto-ADPases, inhibiting further platelet activation via adenosine receptors. The anti-platelet drug Plavix (clopidogrel) inhibits the P2Y12 receptor.


See also


External links



da:ADP

de:Adenosindiphosphat es:Adenosín difosfato id:Adenosin difosfatlt:ADP nl:Adenosinedifosfaatpt:ADP sr:Аденозин дифосфат sh:Adenozin difosfat sv:Adenosindifosfatzh:二磷酸腺苷

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