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(New page: {{ClinPsy}} *ADHD - DRD4)
 
 
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The exact cause of ADHD remains unknown. Research suggests that ADHD arises from a combination of various genes, many of which affect [[dopamine]] transporters.<ref name="dopamine">Roman T, Rohde LA, Hutz MH. (2004). "Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit-hyperactivity disorder." ''American Journal of Pharmacogenomics'' 4(2):83-92 PMID 15059031 </ref>
   
*[[ADHD - DRD4]]
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Suspect genes include:
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* the 10-repeat allele of the [[DAT1]] gene,<ref name="gene">Swanson JM, Flodman P, Kennedy J, et al. "Dopamine Genes and ADHD." ''Neurosci Biobehav Rev.'' 2000 Jan;24(1):21-5. PMID 10654656</ref>
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*the 7-repeat allele of the [[DRD4]] gene,<ref name="gene"/> and
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{{Main|ADHD - DRD4}}
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*the dopamine beta hydroxylase gene (DBH TaqI).<ref>Smith KM, Daly M, Fischer M, et al. "Association of the dopamine beta hydroxylase gene with attention deficit hyperactivity disorder: genetic analysis of the Milwaukee longitudinal study." ''Am J Med Genet B Neuropsychiatr Genet.'' 2003 May 15;119(1):77-85. PMID 12707943</ref>
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-----
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==See also==
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==References & Bibliography==
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<References/>
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==Key texts==
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===Books===
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===Papers===
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==Additional material==
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===Books===
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===Papers===
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*[http://scholar.google.com/scholar?sourceid=mozclient&num=50&scoring=d&ie=utf-8&oe=utf-8&q=ADHD+gene Google Scholar]
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==External links==
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[[Category:ADHD]]
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[[Category:Mental health genetics]]
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{{Psych-stub}}

Latest revision as of 14:05, March 28, 2007

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The exact cause of ADHD remains unknown. Research suggests that ADHD arises from a combination of various genes, many of which affect dopamine transporters.[1]

Suspect genes include:

  • the 10-repeat allele of the DAT1 gene,[2]
  • the 7-repeat allele of the DRD4 gene,[2] and


Main article: ADHD - DRD4
  • the dopamine beta hydroxylase gene (DBH TaqI).[3]

See alsoEdit

References & BibliographyEdit

  1. Roman T, Rohde LA, Hutz MH. (2004). "Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit-hyperactivity disorder." American Journal of Pharmacogenomics 4(2):83-92 PMID 15059031
  2. 2.0 2.1 Swanson JM, Flodman P, Kennedy J, et al. "Dopamine Genes and ADHD." Neurosci Biobehav Rev. 2000 Jan;24(1):21-5. PMID 10654656
  3. Smith KM, Daly M, Fischer M, et al. "Association of the dopamine beta hydroxylase gene with attention deficit hyperactivity disorder: genetic analysis of the Milwaukee longitudinal study." Am J Med Genet B Neuropsychiatr Genet. 2003 May 15;119(1):77-85. PMID 12707943

Key textsEdit

BooksEdit

PapersEdit

Additional materialEdit

BooksEdit

PapersEdit

External linksEdit

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